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The starting point is to address the huge gap in
2019-04-22
The starting point is to address the huge gap in surveillance capabilities identified in 2014 by the WHO\'s first global report on surveillance of antimicrobial resistance. To address this fluvastatin manufacturer gap , WHO\'s action plan is being implemented in phases from early 2016 onwards, gathe
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The estimated annual burden of
2019-04-22
The estimated annual burden of injury in rural Bangladesh revealed by this study was striking; 44 050 deaths and 21 million people suffering major injury events annually that were severe enough for them either to be unable to go to work or school for a day, or severe enough for them to seek treatmen
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Undoubtedly hydroxyurea has a huge potential for improving t
2019-04-20
Undoubtedly, hydroxyurea has a huge potential for improving the quality of lives of people affected by sickle-cell anaemia in settings where frequent and probably unsafe blood transfusions are the current standard of care. However, attention needs to be directed towards the potential adverse effects
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Although Afnan Holmes and colleagues report covers
2019-04-20
Although Afnan-Holmes and colleagues\' report covers substantial ground, several issues remain unexamined. For example, why have facility delivery rates in the country stagnated at roughly 50% over the past decade? Although enhancement of women\'s agency in making health-care decisions is necessary,
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An interphase FISH analysis with
2019-04-20
An interphase FISH analysis with BCR-ABL1-DCDF (dual colour dual fusion) probes (Abbott) showed a normal signal pattern. In addition, an RT-PCR screen with primers specific for the BCR-ABL1 p210 and p190 fusion transcripts and a JAK2V617F mutation analysis were both negative. Chromosomal analysis of
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br How do you manage patients on
2019-04-20
How do you manage patients on intravenous bone-targeted agents who require dental work? For patients who are on IV bisphosphonate therapy and require dento-alveolar procedures there is a suggestion that prophylactic antibiotic use around the procedure may be helpful in reducing ONJ risk [45,49].
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br Case report Radiographs showed a lytic lesion in the
2019-04-20
Case report Radiographs showed a lytic lesion in the left ilium adjacent to the sacroiliac joint (Fig. 1). Computed tomography (CT) (Fig. 2) showed a 5.5×5.0×3.4cm3 lytic lesion in the left ilium; the sacrum was not involved. The lesion was of uniform density with no bone or cartilage matrix form
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In this study all tumors were Campanacci
2019-04-20
In this study, all tumors were Campanacci stage 3, which is a significantly higher proportion than in our database [9]. Such a high stage usually suggests that a tumor is highly aggressive and may be a high-risk factor for lung metastasis. Previous reports have also suggested that the stage of a GCT
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Economic sanctions have exacerbated the
2019-04-20
Economic sanctions have exacerbated the brutality of this conflict many-fold, removing any prospects for peace and reconciliation. We need some reality to gauge their manifold effects before Syria descends into another Iraq, the devastating health consequences of which were well documented. Syria u
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Para refrendar su cr tica al uso descontextualizado
2019-04-20
Para refrendar su crítica al “uso descontextualizado y descontextualizante” de la noción de los ecl, Mato impulsó el cambio de nombre del Grupo de Trabajo BQ-788 sodium salt “Cultura y Poder”, después de su tercera reunión en Caracas en noviembre de 2001, reunión de la cual se derivó una tercera y a
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br For more than a
2019-04-20
For more than a decade, WHO has focused its efforts against infectious diseases in Africa on HIV, tuberculosis, and malaria. HIV benefited from unprecedented efforts to enable diagnosis and prevention of transmission and to provide therapy at low cost. National networks of health clinics, transpor
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br Hacia finales de los a os ochenta y
2019-04-19
Hacia finales de los años ochenta y en el contexto norteamericano, la gran mayoría de las personas que se incluían en la naciente “cultura gay” —habiéndose apropiado previamente de ese término para autodenominarse contra el patologizante apócope de homosexual— eran varones blancos, pequeños burgue
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br Results and discussion In this
2019-04-19
Results and discussion In this study, the np9 and gag mRNA expression was established for 25 patients with CLL (Fig. 1). We found that the transcriptional activity of HERV-K np9 gene in CLL patients was higher than in PBMCs from healthy donors. The results revealed that 18 out of 25 CLL patients
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br Methods br Results Among patients
2019-04-19
Methods Results Among 36 patients with 37 long RP tachycardias, there were 22 patients with 23 ATs (62%) and 14 patients with 14 non-ATs (10 uncommon AVNRTs and 4 PJRTs). Age, sex, and AV Wenckebach palbociclib length at baseline in the EP study were not significantly different between the 2 g
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adiponectin receptor In silico prediction software SIFT Poly
2019-04-19
In silico prediction software, SIFT [51], PolyPhen2 [52], CADD [53], and other prediction systems are useful to evaluate a specific mutation which is detected in a patient. However, even if the in silico software predicts a mutation as pathogenic, we need to examine whether the genetic result is com
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